The spoon flowerseed grows as a perennial shrub in full sun to partial shade. It grows best in moist, well-drained soils and can withstand some drought. Propagation is typically accomplished through seed sowing or cuttings.

Anthospermum spathulatum can easily be reproduced from seeds and does not require any special treatment. This species has been sown and grown under harsh natural conditions at the Tygerberg Hills, where seeds were intentionally dispersed in the field for restoration, letting nature takes its course, and resulted in good germination outcomes. Seeds can be collected in mid to late summer and sown in autumn (April to May). Use a general seed sowing mix with good drainage and aeration. This can include a balanced growth media with sand and sifted compost, peat or potting mix. Ideally, the germination mix should be fine to enhance effective germination, although soil containing coarse particles would not restrict A. spathulatum seeds from germinating. One can choose from varieties of available germination trays to sow seeds. Firmly place seeds on the germination mix and cover them with fine soil particles. Immediately water the seed trays using fine sprayer or mist sprayer to allow seeds to get attached to soil and avoid washing off the seeds on the next watering application. Germination trays should be placed in a semi-shaded area, with some sunlight reaching the area. Trays do not need to be moist all the time, but do not allow them to dry out completely. On average, A. spathulatum seeds germinate in 4 to 8 weeks.

This species has proved to be challenging to propagate by cuttings, but it is doable. Propagation by cuttings was recently tested at Karoo Desert National Botanical Garden and low rooting was recorded. Ideally, fresh cuttings should be collected from a healthy mother plant. Semi-hardwood cuttings should be propagated in autumn. Use a soil mixture with a high ratio of washed coarse river sand mixed with sifted compost. A rooting hormone suitable for semi-hardwood cuttings can be used. Cuttings can be kept inside the controlled greenhouse at a warm temperature, or in the mist house with heated benches and intermittent mist. Supply moisture to the cuttings through misting cuttings trays. It is best to use shallow trays for cuttings, to allow easy drainage and avoid soil holding high moisture content.

Anthospermum spathulatum requires very little maintenance in the nursery. It needs bright, indirect sunlight, a well-draining soil mixture, and moderate watering. During the growing season, fertilize the plant once a month using a balanced fertilizer. This is a relatively fast-growing species, after flowering, trim the plant to maintain control over its size and shape. Pests like mealybugs, scale insects, and spider mites can affect A. spathulatum. Neem oil or insecticidal soap work well against these pests. Additionally, the plant may be impacted by fungal diseases like root rot and powdery mildew. A healthy air circulation system and avoiding overwatering the plant are the best ways to prevent fungal diseases.