The coulter bush is a flowering shrub that is easy to grow and adaptable. It tolerates light frost and can be grown in dry, warm climates. This flowering shrub prefers to grow in spaces exposed to full sun with temperature ranging from 20 to 35°C. The best growth medium for coulter bush is sandy soil that is well-draining and slightly acidic. This species is drought-tolerant and plants can be watered when the soil is almost completely dry however they will perform better with regular watering.

Athanasia trifurcata can easily be reproduced in autumn through seed sowing, or by cuttings. The coulter bush seeds germinate faster with the use of smoke treatment, it is usual with most species that are native to the Fynbos Biome – most specifically those that are found growing in the fynbos vegetation types. In most times, the usual smoke treatment applied includes keeping seeds inside the enclosed tunnel and channel the fire smoke to the tunnel for at least 2 hours, then sow seeds afterwards. Another possible method that can be applied is to smoke seeds by soaking or watering seeds with smoke water. It is always a best practice to derive smoke from fynbos plant material to treat seeds. Coulter bush does not require special treatments to be grown, a general seed sowing mix or fynbos germination mix can be used to sow seeds of this species. Sown seed trays can be placed under light shade and kept moist until they germinate. Germination can take on average between 6–12 weeks. For better germination outcomes, seed trays should not be left to dry out.

Propagations by cuttings can be an alternative method to reproduce Athanasia trifurcata. However, with this species reproducing very well in the wild through seeding, cuttings are not usually done in National Botanical Gardens. Ideally, fresh semi-hardwood cuttings should be collected in autumn from a healthy mother plant and used for propagation. A soil mixture with high sand content that supports good drainage would be suitable to propagate coulter bush by cuttings. Cuttings can be placed and monitored under a light shade shelter, watered with a mist sprayer to avoid soil retaining high moisture.

This species grows well without the use of fertilisers or any other soil supplements. However, where necessary, plants can be fertilised using a balanced organic fertilizer applied early in the growing season. Coulter bush grows well as a dense flowering shrub in the garden with its appealing grey-green leaves and yellow flowers. Dead flowers and branch tips should be pruned prior to the flowering season to give the plant a denser appearance and producing more flowers. This species is not prone to pests and diseases, thus it shows a high resistance to such factors.