The flowers of Colpias last four to five days and are pollinated by a specific Rediviva bee (Hymenoptera, Melittidae). The female bees collect oil and pollen from the flowers, while the males patrol the plants, presumably in search of receptive females. Pollen grains of Colpias are small (± 23 µm), have a semi-reticulate surface pattern (net-like, with holes and walls) and show a tendency to stick together-an adaptation ensuring easy attachment and transfer.

Appendages, called elaiosomes, containing lipid reserves are found on the seeds, and ants are therefore suspected to be responsible for dispersal of seeds to favourable microsites where germination occurs. However, after fertilization, the flower stalks turn away from the sunlight in the direction of the rock. This phenomenon is described as a type of autochory (the plant itself acting as dispersal agent) as the plant seeks a crack where the capsule deposits its seeds. Seeds thus germinate under the same conditions as the mother plant and survival of the species is ensured.