The easiest way to propagate conophytums is by dividing the mother plant. Dig out the mother plant in late summer and divide the individual bodies with roots. Plant them in a container filled with a growth medium suitable for succulent plants, add perlite or sand to increase drainage. The lips plant grows between 2-5 cm in diameter in the wild, but when in gardens they get bigger than that, which is why it is better to use containers that are 10-20 cm wide.

Conophytum pageae prefers sunny areas, but not long hours of direct afternoon sunlight as it burns the leaves. They can however take direct morning sunlight when placed on a windowsill.

They are very hardy plants and can survive temperatures as low as 1.6°C. They prefer an area with good ventilation and low to medium humidity. Add an all purpose fertiliser once a year in autumn. Water regularly during their growing season, autumn and winter. Water must run through the pot and drain out. Excess water must be emptied form the dish or tray on which the pot stands.  

Mix seeds with a teaspoon of fine sand, sow them in autumn and use the same medium used for adult plants. Keep them damp by misting them twice a week and use a fungicide to prevent damping off. They usually germinate in two to four weeks. As the seedlings harden off and take shape, reduce watering and allow the soil to slightly dry out between waterings. Propagation by cuttings can be done anytime during the growing season and no rooting hormone is needed.

Conophytums are not susceptible to many pests and diseases. The number one pest to watch out for is mealy bug. They suck out plant juices from the roots. The most effective method to combat them is to dig out the plants, wash off the soil, cut off any dead roots, soak the roots in a diluted insecticide and repot in clean soil mixed with diatomaceous earth to prevent a secondary infection. The most common cause for root rot in conophytums is due to over watering. Which is why it is important for the roots not to sit in water and to allow the soil to dry out between watering intervals.