This tree with its dense, round crown, is semi-deciduous and makes an ideal shade tree for a small to medium-sized garden. It grows up to ± 15 m in its natural environment, but only about ± 6 m in the home garden and, therefore, makes an ideal shrub as well. Lenticels (a group of cells formed on the outer layer of a plant stem) are a common characteristic found on the young green branches and is usually also covered with interesting star-shaped hairs. The light colour lenticels have a corky texture. The younger branches turn greyish brown as it matures and lack hairs.

The simple, hairy leaves are alternately arranged and is more or less triangularly shaped and it becomes hairless as it matures. The leaf stalk is up to 100 mm long. An interesting feature is the 2 conspicuous glands found at the base of the leaf. The leaf margin appears to be irregular and quite roughly toothed and 4 to 5 pairs of side veins are clearly visible on the underside of the leaf.

The yellowish green flowers appear on ± 80–160 mm long spikes, and male and female flowers are borne separately.

The female flowers appear on the lower part of the inflorescences.

The bright green fruit takes the form of a woody capsule which is about ± 30–40 mm in diameter and contains brown and white-spotted seeds.

The  Croton leuconeurus is similar to C. megalobotrys, but differs in the following ways:
The leaves are single-veined from the base; 8 pairs of lateral veins — in some cases it can be more; the apex is usually broadly tapered and the length of the flower spikes are ± 60–180 mm long. The distribution of the species is restricted to areas surrounding the Victoria Falls in Zimbabwe.