Hippobromus pauciflorus can be easily propagated by seeds. Collect the seeds when the fruits are black, clean the seeds by removing the flesh by hand. Sow the seeds in spring or summer when they are still fresh, in a mixture of potting soil and washed river sand. Place the seed tray under a shade net and not in direct sunlight. Water the seeds three times per week using overhead sprinklers. The seeds take about 3 to 4 weeks to germinate.

Before transplanting the seedlings in to individual pots, it is better to harden them off because outdoor conditions are more harsh than those in the sheltered nursery environment. Gradually expose the seedlings to outdoor conditions for 7 to 14 days before transplanting to avoid damage and failure to thrive. Water the seedlings,  prick them out using a wooden stick, when they have two leaves or are 10 cm long. Handle them gently to avoid damage. Roots of the seedlings should be covered completely. Place the seedlings under a shade net and water them twice a week.

This plant species is fast-growing, resistant to wind and  grows in moist tropical or subtropical regions with rain in summer. It prefers a position in full sun or semi-shade. It is prefers a well-drained, nutrient rich loam or peat soil, but will also do well in a sandy soil with a slightly acidic to neutral pH. Give the plants more water in hot, dry weather and less water in winter. If planted in a nutrient-poor soil, compost and organic fertilizer should be added as well as a layer of mulch to retain the moisture during very dry periods. The root system can quickly become invasive, so it is not advisable to plant it too close to pools, paving, walls and other permanent structures. Pruning should be done in early spring (August) to remove the small twigs around the main stem, to give the plant a pleasing and neat shape.

In warmer areas Hippobromus pauciflorus remains evergreen, and can be used in the garden to provide shade and to attract birds and insects. This plant species is good for screening, in a mixed shrub border, as a windbreaker and to be used for ornamental purposes. It is also suitable for coastal gardens. Plant species like Pappea capensis and Catha edulis will be found in the same habitat with Hippobromus pauciflorus because they share same requirements. This plant species can become invasive, appropriate action should be taken to remove seedlings and suckers.

Larvae of the a number of butterflies feed on the leaves, pesticides should be used to control pests as and when they arise.