Hypoxis membranacea can be propagated asexually and sexually by means of dividing corms and seed sowing. Seeds have high vigour, and therefore, respond very well in cultivation. Sow seeds in summer, on soil mix of sifted fine bark, river sand and sifted compost (3:2:1), or one can use just loam soil. Prepare the seed tray by adding about 1 cm of coarse bark at the bottom of the seed tray to aid drainage, follow up by adding the soil mix and slightly compact the top surface of the mix to prevent uneven growth. No pre-treatment is required, broadcast the seeds direct on the surface, once that is done put a soft spray of water mixed with a sterilizing agent to eradicate any potential pathogens in the soil, such as bacteria, fungi or virus. Place in a cool area with moderate light for germination. Seeds should start germinating in 1 to 2 weeks. 

Dividing corms is one of the best propagation methods for this species; this is best performed in winter. Prepare a general mix including fine bark, river sand and compost (2:1:1), this includes braking off the corms from each other. Divide the corms preferably on mature plants. Transplant the corms to pots or bags preferably 9 cm to 15 cm. Add coarse bark on the bottom of the pot again to improve drainage and add the mix and insert the corms just below the soil mix and not too deep. Place the transplanted corms in light shade with moderate watering, keep the soil moist, but not waterlogged. The leaves should be sprouting within 3 to 4 weeks. 

There are no records of pests or disease attacking H. membranacea, but there are potential threats which have been found on other species in the family. Threatening pests such as African bollworm (Helicoverpa armigera) is often found in H. hemerocallidea attacking the seed pod and damaging the leaves.