This is an easy plant to propagate from both seed and cuttings. The seeds of these plants are very fine and must be collected as soon as they are ripe before they disperse. The best time to sow these seeds will be early spring in order to give them plenty of time to grow before late autumn. Sowing may be done either in seedling containers or directly into the garden.

Ideal cuttings for propagating are semi-hardwood and soft tip cuttings. Cuttings should be planted into river sand and there is no need to apply root-stimulating hormones. Each leaf is capable of producing a new plant when it drops to the ground. The rooted cuttings or seedlings must be planted in dry, shady conditions.

This is a good plant for a low maintenance and waterwise garden. In summer rainfall regions there is no need to water as rain will be sufficient. Kalanchoe rotundifolia will successfully seed itself in the garden and once it is established it will persist for many years.