Although endangered in its natural habitat, cultivating Moraea gigandra presents no great difficulty. The corms are planted in autumn at a depth of about 3 cm in a freely draining medium such as equal parts of river sand and finely sifted, well-decomposed compost. The plants like a very sunny aspect and are most successfully cultivated under cover in deep bulb beds or deep plastic containers with a diameter of 30 cm. In temperate climates they can also be grown in rock garden pockets that are securely lined with wire mesh to exclude moles. In cold climates of the northern hemisphere they are suited to cultivation in the cool greenhouse and must receive bright light for as much of the day as possible. Regular, heavy drenching of the growing medium is required during the winter-growing and spring-flowering periods, but the corms must be kept completely dry throughout the summer-dormant phase.

This species is easily raised from fresh seeds (those harvested the previous season), sown in late autumn in deep seed trays, pots or directly into deep seed beds, in the same medium recommended for mature corms. Seeds should be sown at a depth of 3-4 mm and care should be taken not to sow too thickly, to prevent overcrowding and reduce the chances of loss to damping-off fungi. Germination takes place within six weeks and seedlings should be allowed to grow undisturbed for two seasons before planting them into permanent positions at the beginning of their third season, during which some may flower for the first time, if well grown.

In the southern hemisphere, the flowering period extends from mid September to early October and the flowers only open fully on warm, still days, remaining partially closed in cloudy weather. Individual blooms are somewhat fleeting, each flower lasting only three days, but a succession of blooms are produced by the same plant over a two to three week period. The brilliant display created by a well-grown group of Moraea gigandra plants more than makes up for its rather brief flowering period.

Moraea gigandra is not especially susceptible to pests and diseases although the undersides of the foliage do frequently fall prey to attack by red spider mites as temperatures rise in late spring. Fungal rotting of the corms frequently occurs when they have not been dried out sufficiently during the summer months.