This species shows evidence of horticultural potential, but due to its delicate nature and the difficulty in cultivating, its greatest potential lies in its use as a container plant.

According to Graham Duncan who maintains the bulb collection at Kirstenbosch, Cyrtanthus macmasteri is best grown in pots and needs a very well-drained, sandy medium such as equal parts of coarse river sand and silica (swimming pool) sand, with a 2 cm layer of well-decomposed compost at the bottom of the container. The plants like bright light for the whole day or morning sun and afternoon shade.

Cyrtanthus macmasteri, being deciduous, should be kept as dry as possible in winter and requires a good watering about once per month in summer. It should be noted that this genus is generally not tolerant of severe frost. Cyrtanthus bulbs are not lifted and replanted each year because of their perennial fleshy roots. Once planted, the bulbs should be left undisturbed for several years until they become congested.