Dimorphotheca ecklonis must be planted in full sun in order for the flowers to open to their full potential, although they will tolerate some shade during the day. They can be mass-planted as a groundcover, as a border to a shrubbery, or to line pathways. They can be mixed with the equally attractive D. jucunda whose flowers are totally purple or pinkish mauve with a dark centre.

Cape marguerite can be cultivated from cuttings taken in summer. Seed germinates easily and the plants often sow themselves. They are fast-growing, frost-hardy and drought-resistant. Plants should be cut back after the second year to keep them tidy, or be replaced by new plants. The peak flowering time is in spring but some flowers are always present on the plants throughout summer.

There are no known garden pests that attack these plants.