Gazania krebsiana are very good colonisers, and are also regarded as very good soil stabilisers.  Wild and domesticated herbivores are very fond of these plants.  Gazania krebsiana and other members of the genus are very valuable for grazing, but are often underestimated.  The plants can make a major contribution to the pasture, especially in the dry areas of the winter rainfall region where denuded, trampled patches occur in the veld.  Due to unwise subsistence farming in the Namaqualand region, many Gazania habitats were completely transformed and the plants have become absent from the land.

Apart from the fact that Gazania krebsiana is a palatable plant, there don't seem to be any recorded medicinal uses.  It is a popular garden plant.  it is one of the parent plants for the numerous Gazania hybrids that are offered in many nurseries today.  Gazania krebsiana makes a fantastic garden plant provided it is planted in a sunny area and does not get too much water.  It can be used either individually in beds, as a border plant, in mass plantings, and in window boxes or containers.  The best floral displays can be achieved by planting them in masses like ground covers or by using several species of Gazania together.  There are a number of Gazania subspecies, cultivars, and hybrids available from nurseries, each with its own unique character and colour.

Annual plants that really complement the terracotta gazania well include plants such as Ursinia speciosa, U. cakilefolia, Dimorphotheca pluvialis, D. sinuata, Arctotis hirsuta, Felicia heterophyllo, F. dubia, Senecio elegans, and S. arenarius.  Other perennials are Arctotis stoechadifolia, A. aspera, Felicia ameloides, Osteospermum fruticosum, Scabiosa incisa, Lobelia valida and Geranium incanum.  The more shrub-like plants that are ideal companion plants are the strikingly colourful cushion succulents such as Lampranthus multiradiatus, L. aureus, Ruschia caroli, Drosanthemum speciosum, D. Floribundum and D. striatum.  All these species flower more or less at the same time.  For smaller gardens these plants can be grown in shallow rectangular containers or amongst rocks in a sunny rockery.  It is also very rewarding using different species of Gazania such as G. lichtensteinii, G. rigida, and some of the common varieties such as G. rigens var. leucolaena and var. rigens.  It might not even be necessary to plant them out each year, as they are able to sow themselves and appear spontaneously each year.