Leucospermum bolusii is a good garden subject and an excellent cutflower. It does best in well-drained, acid sandstone soils in a sunny position. Like most members of the protea family, it is intolerant of rich soils and strong doses of chemical fertilizers with high nitrogen (N) and phosphorous (P) content. In heavy clay soils or waterlogged conditions they are more susceptible to infection with the root fungus Phytophthora.

Feed with well-rotted compost, dug into the planting hole and thereafter laid down over the surface of the soil as a thick mulch at least once every year, or in both autumn and again in spring.

Seed germinates easily in late summer - autumn - early winter (March - May). They don't need to be treated with smoke primer to initiate germination, but do respond to the typical autumn hot day and cold night temperature fluctuations. They are usually ready for planting into bags/containers after three to four months.

This pincushion can also be propagated by cuttings. Semi-hardwood tip cuttings or heel cuttings should be taken in late summer - autumn and rooted with bottom heat in a mist unit. A rooting hormone is required for optimal rooting.