This aloe is relatively easy to cultivate under a wide variety of climatic conditions, provided it is planted in a well-drained situation, given adequate water, but not over watered. It can be grown outdoors in raised beds and terraces if sheltered from winter rain. It can also be planted in pots and placed on bright windowsills.

Propagation takes place exclusively by seed, since the plants seldom produces offsets. Sow the seed as soon as possible. The best time would be in the spring or summer, when temperatures are warm. Cover the seeds lightly with a coarse, well-drained sandy soil, and keep moist. To protect the seedlings from fungus, cover them with a fine layer of grit and water from below with a wide long-lasting fungicide. To keep the humidity levels high for the first week or two, cover the pots with a sheet of glass or clear perspex. After a maximum of two weeks, remove the glass or perspex and use a light shade-cloth. For the next two weeks, mist once or twice a day. Most seeds should have germinated by then. Misting can now be reduced to every second and then every third day as the seedlings grow.
When fertilizing, use a light fertilizer specifically formulated for succulents (high potash fertilizer with a dilute low nitrogen), including all micro nutrients and trace elements. Feed them during the growing season. Dilute the fertilizer to ½ the strength recommended on the label. They do very well in poor soils, so a limited amount of fertilizer is in order.
When planting in pots, make sure to use relatively shallow pots to accommodate the fibrous roots, and provide very good drainage. It may stay in the same pot for many years.

Aloe aculeata prefers light shade to full sun. In optimal light conditions, it turns a lovely red or orange. It is semi-frost resistant, but drought-tolerant, and is suitable for xeriscaping. It needs regular watering in summer, but is dormant in winter and needs very little water. After flowering and seeding remove old flower stalks.

When it comes to pests and diseases, the plants are infested by scale and aphids at times and also prone to fungal growth when young. Various products are available at local nurseries to combat these problems.