Ledebouria viscosa is not easily cultivated in the garden and is difficult to maintain in containers away from its natural range. It is best cultivated in terracotta pots in full sun to well-lit, dappled shade, in a warm climate. The bulbs should be planted in a very sandy mineral soil with small amounts of sifted kraal (cattle) manure or well-aged compost added. Watering should be done sparingly and only during the summer growing season. The pots should be completely dried out during the dry winter dormant period. In their natural habitat, the species would receive its rainfall mostly in the form of heavy, late afternoon thundershowers, followed by warm temperatures. They prefer a warm growing season, but can withstand very cold temperatures in winter while the soil is completely dry and the plants are dormant, although temperatures would seldom drop below freezing point. During the dry winter dormancy period, the pots should be moved out of the rain and placed in a dry, cool area with good air movement. Watering can commence at the onset of warmer weather (August to September in South Africa).

Propagation from seed is the best method of producing new plants. Seed must be sown fresh in spring or summer in deep seed trays filled with the sifted potting mixture detailed above. The seed can be sown on a firmly tamped surface and lightly covered with the same mixture about 2 mm deep. The seed trays should be kept in a bright, warm position out of direct sunlight and kept damp for between 2 to 3 weeks, until germination has commenced. Once the seedlings have emerged, watering can be reduced. The seedlings can remain in the seedling tray for many years because of their small adult size, or be planted out at the beginning of their second or third growing season. Flowering size bulbs can be attained after 3 to 5 years.