To date, no records are known to the authors of this species being grown from seed. However, given that this is a fynbos species, and that the biome is, by and large, driven by fire, a starting point to consider when attempting seed propagation, would be the use of smoke or smoke-related products. Soak the seed in smoke-infused water and sow in autumn, using any light and well-draining medium. Cover the small seeds with a thin layer of sand or fine-milled bark and then water. Sufficient light and ventilation of the space where you house the sowing-tray are crucial. Do not overwater or allow the tray to totally dry out. Although the time to germination for this species is unknown, expect germination from the third week. The appearance of the first true leaves signifies that potting can commence. 

At Kirstenbosch, this species is propagated vegetatively by cuttings taken in autumn, although trials in other seasons can also be considered. Take cuttings of between 25 and 55 mm length, from the current year’s new growth. Remove roughly a third of the foliage, cut below the node and dip in a rooting hormone. The rooting medium is a 50 % mixture of bark and perlite, but this can vary according to what is available. The cuttings are placed on a heated bench under a mist-unit. Rooted cuttings are shifted to a hardening-off section for about 2 weeks after which potting can commence.

Potted plants are placed in a shady section for 2 weeks up to a month and then moved to full sun. This is a good time to pinch out the growing tips of the seedlings, or to prune plants grown from cuttings, to facilitate a more bushy growth habit.

Acmadenia alternifolia thrives in full sun and well-drained soil. Autumn and winter, which is the rainy season in the Fynbos Biome, is the preferred planting time. Planting with the rain ensures that plants have a good chance of establishing themselves in the garden before the onslaught of the dry, heat of summer. Generally, with buchus, maintaining planting intervals of 200–300 mm is deemed adequate as it provides ample space to encourage growth. Such dense planting help plants to better cope with dry spells by retaining soil moisture. Provide a good thorough watering in autumn and winter once planted, and continue watering regularly if the rainy season is not yet in full swing. Irrigation during the late spring to summer should be kept to a minimum, however, care must be taken not to allow plants to dry out totally. A generous layer of well-sterilized mulch will also go a long way in ensuring soil moisture is being retained.

This buchu is best suited to fynbos and coastal gardens. Plant it with other fynbos plants such as: Pelargonium cucullatum, P. suburbanum, P. betulinum and P. capitatum, Passerina corymbosa and P. intermedia, Coleonema album and C. pulchellum, Agathosma serpyllacea, A. apiculata and A. ovata, Salvia aurea, Leonotis ocymifolia and L. leonurus, Metalasia muricata and M. densa, Helichrysum felinum, Leucospermum cuneiforme, Leucadendron salignum and L. eucalyptifolium, Protea cynaroides, Thamnochortus cinereus, Geranium incanum, Seriphium plumosum, Anthospermum aethiopicum, Berzelia intermedia, Erica diaphana and E. glandulosa subsp fourcadei.