Ficus burkei can be propagated from seed or semi hardwood cuttings, though seeds are generally more reliable for large scale planting. Collect ripe figs in late summer to autumn and extract the seeds by gently mashing the fruit and rinsing away the pulp. Sow seeds immediately, as viability drops quickly. Use a well-drained propagation medium, such as equal parts river sand, compost and peat or coir. Seeds should be sown on the surface and lightly covered to keep the medium moist but not waterlogged. Germination typically occurs in 2 to 4 weeks in warm conditions, ideally 20 to 25°C and seedlings should be pricked out when they develop two to three true leaves.

Semi-hardwood cuttings can be taken in spring, 15 to 20 cm long, treated with a rooting hormone and planted in a sandy-loam medium under mist or high humidity conditions. Cuttings may root in 6–10 weeks. After seedlings or cuttings are established, harden them off for 2–3 weeks before planting in the garden.

Ficus burkei grows best in full sun to light shade, with a preference for well-drained, fertile loam soils, though it tolerates sandy or rocky soils. Moderate watering is required, especially during establishment, with less frequent irrigation once the tree is mature. A dry period in winter helps maintain compact growth and fruit production. Apply balanced organic compost or slow release fertiliser in spring, avoiding excessive nitrogen, which can reduce fig production. Mulch around the base to conserve moisture and suppress weeds. The species is tolerant of occasional frost and harsh conditions and it grows fast, potentially reaching 6–12 m in height in favorable conditions. Prune lightly after fruiting to maintain shape, remove dead branches and encourage a dense canopy. Avoid planting near foundations or paved areas, as aerial and lateral roots can be aggressive and figs can stain paving with fallen fruit.

Ficus burkei makes an excellent feature or focal point tree, especially in naturalistic or wildlife friendly gardens. Its dense canopy provides shade, making it suitable near seating areas or as a street or avenue tree. In botanical gardens, it can be planted near paths to highlight wildlife interactions with its figs, and its tolerance of dry periods makes it suitable for water wise gardening.

Ficus burkei is a strong, easy to grow tree that usually does not have many pest problems but young seedlings can occasionally be affected by fungal damping off, which can be prevented by using well drained soil and fungicide treatments if necessary. Aphids or scale insects may occasionally colonise young shoots which can be controlled by using general horticultural oil or insecticidal soap.