These plants should be grown in sunny, somewhat sheltered and well drained areas. They are ideal plants for a difficult or neglected part of the garden and with the addition of other suitable plants can create stunning rock gardens. Companion plants such as Cotyledon orbiculata, Tylecodon paniculatus, Crassula arborescens, Aloe dichotoma, Aloe brevifolia, Pelargonium crithmifolium, Pelargonium sericifolia, etc., are ideal to start a rock garden.

Aloe microstigma is best grown from fresh seeds that are sown in summer or autumn. A coarse sandy medium must be used and seeds are sprinkled lightly and covered slightly with sand. If kept moist, (not wet) seeds germinate within two weeks. The most common pests on Aloe microstigma are scale, the aloe snout beetle, and aphids. These can all be successfully treated with contact or systemic pesticides. If plants are to be fed, use only organic based fertilisers in a liquid solution. These can be applied as a soil drench or sprayed on plants once a month. Another good plant food for aloes is bone meal. Bone meal is mixed in the soil and works wonders especially when planting or transplanting aloes.