Most species from this genus are quite hardy plants, including this one, so it will be able to withstand most weather conditions. It is a naturally neat plant, but specimens can be pruned to stimulate new growth and to shape the plant for topiaries. It can also safely be planted close to pools, paving, walls, and other permanent structures as the roots are not invasive. At Kirstenbosch, it was one of the species planted against the north-facing gabion walls in the nursery, which were chosen because they have the ability to thrive in hot, exposed conditions, and have a natural tendency to scramble and produce adventitious roots. The plants cover and screen the stark walks, and over time their branches and roots take the place of the wire baskets, thus stabilizing the bank even if the wire corrodes. Pavetta zeyheri has flourished on these walls. It is also easy to manipulate by pruning.

Propagate by seed and cuttings. Seeds may be sown in spring or early summer, in a seed tray, in a well-drained, well-aerated soil mix. Take semi-hardwood cuttings in spring to early summer and dip in rooting hormone number 2 or 3 to stimulate root development. The growth medium should be well-aerated and able to hold the cutting firmly while staying moist. All potting equipment needs to be sterilized to prevent fungal infections and other diseases affecting the plant and inhibiting its growth.

Air layering may also be done to propagate the plant. Air layering is a method of propagating new trees and shrubs from stems still attached to the parent plant. The stem is wrapped with damp moss to encourage roots to form.

Pavetta zeyheri grows well in full sun, in fertile and well-drained soils. It is water wise and hardy. Flowers may be used in flower arrangements and kept in a vase at home. Its small size makes it ideal to grow in a smaller garden, whether as shrub or small tree, and perfect for containers. It will attract birdlife and other insects, because it produces fruits edible to birds. Add organic matter, such as mulch and compost, to the soil once every season to make it fertile.