Secamone alpini can be propagated by seed, sown in spring in summer-rainfall regions and in autumn in winter-rainfall regions. Collect the fruits just as they start to split open, before the seeds blow away. Remove the tuft of silky hairs before sowing to prevent the seeds from blowing away. Use a sandy, well-drained soil mix, lightly cover the seeds, place the tray in a warm, well-ventilated, well-lit place and keep moist. Transplant the seedlings after their first pair of true leaves have developed.

Secamone alpini is best grown in full sun and well-drained, composted soil. Moderate water can be given all year. This species is adapted to survive in a wide range of habitats, mostly frost-free with rainfall in summer or winter or all year. It should require minimal additional water once established and it will tolerate periods of drought, but will perform best with regular watering. In a container, Secamone alpini grows best in well-draining soil, which also helps prevent root rot – a common problem caused by overwatering.