Struthiola myrsinites is an open, willowy shrub which grows to a height of 2 m. The branches are tetragonal. It grows in both full sun and light shade, and can be found in bloom at any time of the year. The white or rarely pale pink flowers have a long, very narrow tube, topped with 8 finger-like petals. They are sweetly scented during the evening and attract moths as pollinators. It is this characteristic which gives rise to its common name which translates as 'little-lady-gad-about-at night.' A small sprig of flowers will perfume an entire room in the evening. The leaves are opposite, narrowly elliptic and acute.

The flowers have a well-developed calyx with 4 or 5 lobes, often resembling petals. The petals are absent or reduced to scale-like or fleshy lobes at the mouth of the calyx.