Treculia africana can be propagated by seeds, cuttings, budding and shield grafting. The seeds should be collected, cleaned to remove impurities and sown when they are still fresh. The highly recommended sowing mix is medium sand and fine sand. Keep the seed trays moist and warm. Germination will start after 9 days. Seedlings should be transplanted after four weeks into topsoil mixed with poultry manure, in individual pots and placed under 80% shade netting. Seedlings should be watered three times a week in summer and twice a week in winter.

Stem cuttings should be taken from a 1 year old mother plant, using a sharp and clean cutting tool, and treated with growth hormones to stimulate root development. Treculia africana stem cuttings should be propagated in a medium river sand.

Treculia africana usually grows in full shade or part shade in a forest, in a clay soil or medium loamy soil with a pH of 5.0 to 7.5. At Lowveld National Botanical Garden this plant species grows in full sun in a loamy soil. The water requirement for this plant species when it is established is moderate and it can tolerate water stress but seedlings require frequent irrigation at least twice a day. Organic fertilizer should be applied twice a year for optimum growth.

Treculia africana is not recommended to be planted next to the house because the large fruits falling from the tree can cause injury to humans and damage to the property. Treculia africana can be used as wind breaker against storm and as flood control. In terms of water and sun requirements, Treculia africana can be planted together with Anthocleista grandiflora, Syzygium cordatum, Breonadia salicina and Raphia australis.

This plant is prone to fungal diseases which cause fruit rot, which drastically reduces the yield of Treculia africana and can be treated with an appropriate fungicide. Seeds stored at a temperature of 30–35°C are at risk of rotting.