Dwarf buffalo-thorn is not so popular in cultivation. However, it holds great potential to become a garden plant, mostly for its foliage. Ziziphus zeyheriana is a slow-growing shrub, however, also very hardy and long lived, as it can with stand very harsh conditions such as extreme heat, low temperatures, frost and drought, making it a great low-maintenance, water-wise garden plant.

Successful propagation can be achieved through seeds (sexual propagation) and cuttings (vegetative propagation). Collect seeds once ripened and sow them fresh, however, first clean the seeds by removing the pulp and soak the nut in hot water for 24 hours to soften the coat. Once the coat is soft remove the seed inside and sow it in any well-drained soil, such as loam or river sand. To achieve this use any seed tray, fill it up with well-drained soil, preferably river sand or loam soil, prepare a by adding a thin layer of coarse bark a the base of the seed tray and add either river sand or loam soil and slightly compact the soil to make it firm. Using a watering can with a solution of a horticultural-approved detergent to eliminate pathogens. Press your seeds slightly below the surface and place them in a well-ventilated area and keep them moist but not wet, water once or twice a week. The seeds should germinate within 3 to 4 weeks.

For vegetative propagation, collect cuttings in the early morning or afternoon, when then the plant is at its full vigour. Prepare cuttings of about 5 to 10 cm long, make the cut below a node and dip the cutting in rooting hormone, preferably hardwood hormone. Insert the cuttings in a mixture of 1 part sifted fine bark, 1 part sifted compost and 2 parts perlite, for sufficient rooting. Keep them in a warm and humid area, with temperatures ranging from 25 to 27℃. Rooting should take place within 2 to 3 weeks.

There are no pests or diseases recorded to attack this species in particular, however there are many pests and pathogens that one should be aware of, such as root rot disease, Polyphagous Shot Hole Borer or any of the other common garden pests, such as aphids, mealy bugs, spider mites etc.