Although L. viridiflora is one of the rarest members of this genus in the wild, it is one of the easiest to grow and is being cultivated in specialist bulb collections all over the world. It is most suitably grown as a container subject in a very well-drained medium such as equal parts of coarse river sand or silica sand (swimming pool sand), and finely sifted acid compost or finely milled acid bark. In the Southern Hemisphere it grows best in plastic pots (20-25 cm diam.) placed in a position preferably receiving full morning sun and afternoon shade. In cold climates of the Northern Hemisphere, it does well in terracotta pots and requires the protection of the cool greenhouse as it is frost tender.

The bulbs are planted in early autumn at a depth of 1-2 cm below soil level and should be watered well and then not again until the leaf shoots appear, after which a good drench once per week is suggested. Offsets develop readily and these can be removed when large enough during the summer dormant period.

Seeds form easily after hand pollination and are sown 3-4 mm below the soil surface in mid-autumn in the same medium recommended for mature bulbs. Take care not to sow too thickly to prevent the occurrence of damping-off fungi, and water the seedlings with a fine spray every few days. Germination of fresh seeds occurs within two to three weeks, and the seedlings usually flower for the first time in their third year or sometimes even in their second year under ideal conditions.

L. viridiflora can also be propagated by leaf cuttings. Both the upper and lower portions of the leaf can be used for this purpose and it is done by cutting off a whole leaf at the very base, just below soil level, and then cutting it in half. Place the cuttings in slightly damp river sand in deep seed trays so that the lower 20 mm rests below the surface, and place in a lightly shaded but well-aerated aspect. After about one month bulblets begin to form that can be separated during the summer dormant period and planted out in the normal way the following autumn.

The bulbs of all Lachenalia species, especially L. viridiflora, are highly susceptible to attack by mealy bug, causing them to disintegrate, and slugs and snails are very partial to the foliage.