The orchids in the Disa uniflora group are said to be comparatively easy to grow and are by far the best known group of disas when it comes to the cultivation of orchids. Species occurring in wet conditions, such as that of Disa nivea, can be difficult to cultivate as they can get killed by rot in cultivation. Although specific information on how to grow Disa nivea could not be found, the following rules are applicable to all disas and local orchid societies can be contacted to purchase seeds from which this beautiful disa can be grown.

Disas in general require a very well-drained medium, such as washed, coarse river sand or silicon sand, with 10% peat added. It is important that the growing medium should not break down when kept moist, but should be able to remain aerated, and maintain a slightly acidic pH. Roots must never be allowed to dry out, but over watering and sogginess should be avoided at all times, as free drainage is critical. It was found that drip irrigation improved biomass accumulation, compared to ebb-and-flood irrigation. Temperature in the root zone must be kept between 5 and 15ºC in winter and 10 and 20ºC in summer. Ambient summer temperatures of above 30ºC can be tolerated, as long as the pots and roots are kept cool. Disas are prone to fungal infections, but bacterial diseases are not seen as a problem and no viruses have been identified yet.