Melolobium subspicatum is threatened in the wild and not commonly cultivated. It can be successfully propagated and grown under controlled or natural conditions. Seed propagation is the most reliable method. Collect seeds from mature pods in late summer or autumn. The seeds are hard-coated and germinate better after pre-treatment. Scarify the seeds before planting to improve germination, either by lightly cutting the seed coat with a blade or by soaking the seeds in warm water for 12-24 hours. Sow seeds in a well-draining seedling mix, such as sand mixed with compost or loam, planting them about 1 cm deep. Keep the seed tray moist but not waterlogged and place it in a warm environment. Germination typically occurs within 2-3 weeks. Transplant seedlings once they have well-developed roots.

Melolobium subspicatum can also be propagated through stem cuttings, although this method is less reliable. Take semi-hardwood cuttings in late spring or early summer. Apply rooting hormone to stimulate root growth and place the cuttings in a well-draining propagation mix. Keep the medium moist and maintain high humidity (e.g., in a mist house or under plastic) until roots form.