Nerine humilis and N. sarniensis are particularly effective when planted in large groups in rockery pockets. It is best to leave established bulbs untouched for at least five years as they don't like to be disturbed. Only when plants have become too overcrowded and the flowering has deteriorated, should plants be moved and divided. The plants also make excellent container subjects and can be used together with N. sarniensis on a sunny patio, or in sunny window boxes.

Excellent water-holding capacity, as well as perfect drainage of the growing medium, are two of the most important factors when cultivating nerines, especially in containers. Ideally one should use a sandy soil with a little bit of compost and with a slightly acidic pH. For containers, the best soil mix is equal parts of river sand, silica sand and finely sifted compost. The bulbs of N. humilis can be planted with their necks slightly above, or at soil level. Water the plants once a week from early autumn until early summer, followed by a completely dry summer dormant period.

The best and easiest way to propagate N. humilis is by means of seeds, which ripen in summer. The seeds are sown in deep seed trays in a well-drained mixture such as equal parts of river sand, silica sand (swimming pool sand), and finely sifted compost. Sprinkle seeds evenly over the surface and cover them with a thin layer of the same mixture. Watering with a fine rose is ideal. When the first leaves appear, water only once every two to three weeks. The little N. humilis seedlings should then be kept dry during summer. Another way of increasing the plants is simply to divide those groups that have become too crowded.

The most important pest encountered with nerines is the lily borer, otherwise known as the amaryllis caterpillar. The tiny caterpillars bore into the leaf, flower or stem tissue and, if left unchecked, will bore into and consume the bulb itself. Spraying plants with a carbaryl-based insecticide usually takes care of the problem. Mealy bugs, thrips and snout beetles are other pests that attack nerines. They can form large colonies and often transmit viral diseases. An effective insecticide used as a drench should eradicate the problem.