The grey cabbage tree is relatively easily cultivated, but does not tolerate extreme frost. It is highly desirable as an accent plant in the landscape or as a sculptural individual specimen placed in the ideal position. It requires well-drained soil and a warm garden, it can tolerate more water in the garden than what it gets in the wild and makes a lovely garden subject. Unfortunately, it is seldom used and rarely found available in nurseries. The seed should be harvested and sown fresh. After washing the thin layer of pulp off the seed it should be sown immediately into seed trays in a fine seedling germination mixture and covered lightly. Seed may take from three to eight weeks to germinate. Seedlings are best left in the tray for the first year and transplanted into individual containers at the beginning of the second growing season.

Saplings respond well to horticultural fertilizers, they grow quickly and may be ready for planting into the ground after three to five years in the nursery. When planting out, trees respond well to a well-prepared hole with plenty of compost and bonemeal mixed with the soil.

All cussonias have potentially destructive root systems and should therefore be kept a distance from any structural features and underground services such as sewer pipes, water mains and electrical cables. Cussonias do not generally transplant well once they are established, so the position needs to be chosen carefully.

Cussonias are sometimes prone to being plagued with psylla, a small insect that causes pimple-like growths on the leaves, causing the leaves to be distorted and unsightly. This can be controlled with the use of a systemic insecticide.