Pentzia incana can be propagated vegetatively by taking heel and stem cuttings from slightly hardened new growth. A rooting hormone suitable for semi-hardwood cuttings can be used. Cuttings are placed in a well-drained propagation medium, such as river sand or fine-milled bark. Place cuttings in a propagation house with adequate lighting, good airflow, humidity and bottom heating to achieve a high rooting percentage. Cuttings must be checked on a regular basis because too much watering can cause this arid species to rot.

In a study conducted to observe the root systems of Pentzia incana, the species was described to have an extensive root system as it is stoloniferous. Stolons root easily when touching the ground under favourable conditions and can be used as a propagation method.

Seeds can be sown in autumn using a well-drained potting medium. Germinated seedlings must be monitored until they are large enough to be transplanted into containers of suitable size relative to the young plant.

This is a fast-growing, water-wise plant that can be enhanced with proper pruning when necessary. It is a good groundcover or filler in the garden and shows potential as a small hedge.

Plants growing in full sun conditions have been observed to be pest-free, while those subjected to semi-shade conditions during the afternoon are at times covered with aphids.

There are several species which share a habitat with the Anchor Karoo and make good companion plants in the garden, this may include: Aloe arborescens and A. ferox, Crassula perforata, Carpobrotus acinaciformis, Curio crassulifolius, Carissa bispinosa subsp. bispinosa, Dicerothamnus rhinocerotis, Eriocephalus africanus var. africanus, Plecostachys serpyllifolia, Chrysocoma ciliata and C. coma-aurea, Felicia filifolia subsp. filifolia and F. flanaganii, Freylinia undulata, Helichrysum cymosum, Dodonaea viscosa var. angustifolia, Euclea undulata, Pelargonium abrotanifolium, Pteronia incana, Seriphium plumosum, Arctotheca calendula, Cotula nudicaulis, Leysera tenella, Nemesia cheiranthus, Senecio arenarius, Agathosma apiculata and Oscularia vredenburgensis.